Seroatlas · Human Serome Atlas

A8MTW9

Putative uncharacterized protein ENSP00000380674

Also known as: YB043_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A8MTW9
Gene: A8MTW9
Canonical length: 85 aa

OverviewNCBI Gene

No narrative summary is available for A8MTW9 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

85 residues, UniProt reviewed canonical sequence.

>A8MTW9|A8MTW9
     1  MRPLLCALAG LALLCAVGAL ADGREDRGSP GDTGERPAGP ARGPGLEPAR GTLQPRPRPP
    61  RKRWLLSPGA GAQQLEVVHL PGSTL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against A8MTW9 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.69

OntologyGO

Cellular components

extracellular region

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads A8MTW9 as an antibody target. Whether an autoantibody or antibody against A8MTW9 could matter depends on whether native A8MTW9 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

A8MTW9 is annotated as secreted, so native A8MTW9 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label A8MTW9 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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