Seroatlas · Human Serome Atlas

A8MT66

Putative uncharacterized protein ENSP00000383407

Also known as: YU005_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A8MT66
Gene: A8MT66
Canonical length: 165 aa

OverviewNCBI Gene

No narrative summary is available for A8MT66 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

165 residues, UniProt reviewed canonical sequence.

>A8MT66|A8MT66
     1  MNLFCISLEG SMDSLYEPIP EQQANQENMS SRTDSPIPPF GESEQTPNNL FVGVSNLENA
    61  KPKKRKLFRR FMSENKIFEG KTVNDKIWQE HSKHKNDSHI RRPCQLKDLN ENDFLSNNIH
   121  TYQGKTLQGT SYQVTSECWS PFHYQRHVET TVDELVRHFF PDVTI

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against A8MT66 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.71

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads A8MT66 as an antibody target. Whether an autoantibody or antibody against A8MT66 could matter depends on whether native A8MT66 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

A8MT66 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label A8MT66 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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