Seroatlas · Human Serome Atlas

A6NJR5

Putative speedy protein-like protein 3

Also known as: SPDL3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NJR5
Gene: A6NJR5
Canonical length: 290 aa

OverviewNCBI Gene

No narrative summary is available for A6NJR5 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

290 residues, UniProt reviewed canonical sequence.

>A6NJR5|A6NJR5
     1  MQKHYTVAWF LYSAPGVDPS PPCRSLGWKR KKEWSDESEE EPEKELAPEP EETWVVEMLC
    61  GLKMKLKQQR VSPILPEHHK DFNSQLAPGV DPSPPHRSFC WKRKREWWDE SEESLEEEPR
   121  KVLAPEPEEI WVAEMLCGLK MKLKRRRVSL VLPEHHEAFN RLLEDPVIKR FLAWDKDLRV
   181  SDKYLLAMVI AYFSRAGLPS WQYQRIHFFL ALYLANDMEE DDEDPKQNIF YFLYGKTRSR
   241  IPLIALFQKL RFQFFCSMSG RAWVSREELE EIQAYDPEHW VWARDRARLS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against A6NJR5 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.48

OntologyGO

Molecular functions

protein kinase binding

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads A6NJR5 as an antibody target. Whether an autoantibody or antibody against A6NJR5 could matter depends on whether native A6NJR5 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

A6NJR5 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label A6NJR5 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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