A6NHS1
Putative uncharacterized protein ENSP00000347057
Also known as: YK042_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for A6NHS1 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
94 residues, UniProt reviewed canonical sequence.
>A6NHS1|A6NHS1
1 MVLLAGTRPQ GGEARCMIPP PPSPLLGAQV EEDRTEFKEF QDFSSLPDTR SVASDDSLYP
61 FQDEEEHGVE GVESVPEEGI LEAWGSCGRW CGVGLocalizationUniProt · AlphaFold · HPA
Whether an antibody against A6NHS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.72
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads A6NHS1 as an antibody target. Whether an autoantibody or antibody against A6NHS1 could matter depends on whether native A6NHS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
A6NHS1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label A6NHS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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