Seroatlas · Human Serome Atlas

A6NDX4

Putative transmembrane protein ENSP00000320207

Also known as: YO011_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NDX4
Gene: A6NDX4
Canonical length: 124 aa

OverviewNCBI Gene

No narrative summary is available for A6NDX4 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

124 residues, UniProt reviewed canonical sequence.

>A6NDX4|A6NDX4
     1  MYVSISFLLG LSHLVLCCLL TFIVNFYLPP ESIDFEFMAH NWSKGRSPSS TLGLSWFKAG
    61  FRFSDGWSMF YSSGLPGVAL PGSPPRSHLL PGTQILIRSF QPCESAKHSA RLSSLLTTTS
   121  YSVS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against A6NDX4 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 1
Mean surface accessibility (rSASA): 0.51

OntologyGO

Cellular components

membrane

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads A6NDX4 as an antibody target. Whether an autoantibody or antibody against A6NDX4 could matter depends on whether native A6NDX4 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

A6NDX4 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label A6NDX4 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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