Seroatlas · Human Serome Atlas

A4D1N5

Putative uncharacterized protein FLJ40288

Also known as: YG018_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A4D1N5
Gene: A4D1N5
Canonical length: 150 aa

OverviewNCBI Gene

No narrative summary is available for A4D1N5 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

150 residues, UniProt reviewed canonical sequence.

>A4D1N5|A4D1N5
     1  MSSRRSSLSP WKCPWFVYCF ERPISREAGP VVHQSPTVLY LHSELAARQT QGRLLPREPA
    61  AEDLRLSLPG GHAALGLFKL QGKDSYPHPP TVLLGEDLSS SGWNSWVFGI LNISRDEEAI
   121  GILTTILQLR ETESSAVKWT HTKHSRELGP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against A4D1N5 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.46

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads A4D1N5 as an antibody target. Whether an autoantibody or antibody against A4D1N5 could matter depends on whether native A4D1N5 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

A4D1N5 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label A4D1N5 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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