Seroatlas · Human Serome Atlas

A1L4Q6

Putative uncharacterized protein FLJ41423

Also known as: YK033_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A1L4Q6
Gene: A1L4Q6
Canonical length: 167 aa

OverviewNCBI Gene

No narrative summary is available for A1L4Q6 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

167 residues, UniProt reviewed canonical sequence.

>A1L4Q6|A1L4Q6
     1  MAALSSRCPR SAAGPAYLQE AARSAHWASP PLVPLRTFQS SLFSSGSFHS REEEEEGVSL
    61  LRTALVGQGP VPLFLGSLFC AGCRQGPSVW SCGEPVPRRI WVTASVTPSP RQALHPCSDS
   121  LDILKALHLL PAAFSPFIWV QVFAEPSNKE SRGENDGGEE RESANIY

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against A1L4Q6 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.54

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads A1L4Q6 as an antibody target. Whether an autoantibody or antibody against A1L4Q6 could matter depends on whether native A1L4Q6 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

A1L4Q6 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label A1L4Q6 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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