Cation transport ATPase (P-type)
IPR050510
Definition
The cation transport ATPase (P-type) family is responsible for the active transport of cations across cellular membranes, utilizing ATP hydrolysis to drive the exchange of ions such as sodium, potassium, and hydrogen. Members of the family create electrochemical gradients essential for nutrient transport, cellular homeostasis, and various physiological processes including gastric acidification and sperm motility. Some subunits are regulated by cardiac glycosides like ouabain and are involved in maintaining electrolyte balance in epithelial cells of the kidney, colon, and airway epithelium.
6 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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