Keratin-associated protein, type8/19/20/21/22

Definition

The major structural proteins of mammalian hair are the hair keratin intermediate filaments (KIFs) and the keratin-associated proteins (KRTAPs). In the hair cortex, hair keratins are embedded in an inter-filamentous matrix consisting of KRTAPs which are essential for the formation of a rigid and resistant hair shaft as a result of disulphide bonds between cysteine residues. There are essentially three groups of KRTAPs, viz: the high-sulphur (HS) and ultra-high-sulphur (UHS) KRTAPs (cysteine content: 16-30 and >30 mol%, respectively) and the high-glycine/tyrosine (HGT: 35-60 mol% glycine and tyrosine) KRTAPs.

13 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (13 proteins: gene, accession, name)

• KRTAP19-1
• KRTAP19-2
• KRTAP19-3
• KRTAP19-4
• KRTAP19-5
• KRTAP19-6
• KRTAP19-7
• KRTAP19-8
• KRTAP20-1
• KRTAP20-2
• KRTAP21-2
• KRTAP22-1
• KRTAP8-1